Biological Engineering (2016- Present)
My current research at IITGn focuses on understanding the molecular mechanisms underlying Alzheimer’s disease (AD), a devastating neurodegenerative disorder causing progressive neuronal deaths every year. Neuritic plaques related to amyloid-beta peptide (Aβ) and neurofibrillary tangles (NFT) due to Tau protein in neurons are pathological hallmarks of the AD. Studying these essential proteins could help us find preventive measures and the possible way to cure the disease completely. My experimental approach is to somehow stop the aggregation of tau either by designing inhibitors synthetically that will destabilize the protein or by medicinal chemistry search that will help us find novel molecules for treatment.
In the long term, I foresee myself as a successful scientist promoting a healthy working environment that will help me and my associates to contribute towards the progress of humankind at large. In my leisure hours, I play cricket, football, watch movies and listen to music. Besides, traveling has made me independent and has improved my self-confidence. Adventure sports, photography and trekking excites me a lot.
I am Pravin Hivare, and I am a Ph.D. scholar in the department of biological engineering at IITGn. I joined the Institute in July 2016. I hail from a tiny village called ‘Dhagpimpari’, in the Osmanabad district of Maharashtra. I have completed my bachelor and master in biotechnology from Fergusson College, Pune. My master’s project dealt with medical and environmental applications of metal nanoparticles.
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